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Meat Lovers Pizza Casserole

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This Meat Lovers Pizza Casserole combines all your favorite pizza toppings into a cheesy, hearty casserole. Featuring layers of savory meats, zesty marinara sauce, and gooey cheese, this is the perfect dish for pizza lovers. Easy to make and absolutely delicious, it’s the ultimate comfort food.

Ingredients

  • 12 oz pasta (penne or rotini)
  • 1 lb ground beef
  • 1/2 lb Italian sausage, crumbled
  • 1/2 cup pepperoni slices
  • 2 cups marinara or pizza sauce
  • 1 tsp Italian seasoning
  • 2 cups shredded mozzarella cheese
  • 1/2 cup shredded cheddar cheese
  • 1/4 cup grated Parmesan cheese
  • 1/2 tsp garlic powder
  • 1/2 tsp red pepper flakes (optional)

Instructions

  • Cook the Pasta: Cook the pasta according to package instructions. Drain and set aside.
  • Prepare the Meat: In a large skillet, cook the ground beef and Italian sausage over medium heat until browned and fully cooked. Drain any excess fat.
  • Combine the Ingredients: Preheat your oven to 375°F (190°C). In a large mixing bowl, combine the cooked pasta, meat mixture, pepperoni, marinara or pizza sauce, Italian seasoning, garlic powder, and red pepper flakes (if using). Stir to combine.
  • Assemble the Casserole: Transfer the mixture to a greased 9x13-inch baking dish. Top with shredded mozzarella, cheddar, and Parmesan cheeses.
  • Bake: Bake for 20-25 minutes, or until the cheese is melted and bubbly.
  • Serve: Let the casserole cool for a few minutes, then slice and serve.

Notes

  • Storage: Leftovers can be stored in an airtight container in the fridge for up to 3-4 days.
  • Reheating: Reheat in the oven at 350°F (175°C) for about 10-15 minutes or in the microwave for individual servings.
  • Variations: Add veggies like bell peppers, onions, or mushrooms for more color and nutrition. For a spicier kick, increase red pepper flakes or add jalapeños.1